Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174316 | 0.95 | ALDH1A1 (0.34) | S1PR1S1PR3PIM1ALDH1A1HSD17B10 | |
| SCHEMBL20174347 | 0.92 | MAPK1 (0.33) | ALDH1A1HSD17B10KDM4EATMMAPT | |
| SCHEMBL20174324 | 0.92 | MAPT (0.35) | PIM1ALDH1A1HSD17B10KDM4EATM | |
| SCHEMBL20174352 | 0.92 | ALDH1A1 (0.34) | ALDH1A1HSD17B10KDM4EATMCYP1A2 | |
| SCHEMBL20174356 | 0.91 | KMT2A (0.36) | PIM1ALDH1A1HSD17B10KDM4EATM | |
| SCHEMBL20174400 | 0.90 | S1PR1 (0.34) | S1PR1S1PR3ALDH1A1HSD17B10KDM4E | |
| SCHEMBL20174355 | 0.87 | KMT2A (0.33) | ALDH1A1HSD17B10KDM4EATMCYP1A2 | |
| SCHEMBL20174326 | 0.86 | MAPK1 (0.33) | ALDH1A1HSD17B10KDM4EATMMAPT | |
| SCHEMBL20174323 | 0.86 | MAPK1 (0.33) | ALDH1A1HSD17B10KDM4EATMMAPT | |
| SCHEMBL20174723 | 0.86 | ALDH1A1 (0.34) | ALDH1A1HSD17B10KDM4EATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | S1PR1 2330/4885S1PR3 2837/4885PIM1 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.