SCHEMBL22326642

SCHEMBL22326642

CC(C)C(=NOCc1ccc(Cl)cc1)C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
IDO1 P14902 2/20 0.42
AGXT P21549 2/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP2 P08253 1/20 0.42
CA9 Q16790 1/20 0.42
PPARG P37231 3/20 0.40
PPARA Q07869 3/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22326643 0.84 AGXT (0.44) L3MBTL1MAPTIDO1AGXTCA1
SCHEMBL10147075 0.81 MAPT (0.45) L3MBTL1MAPTIDO1PPARGPPARA
SCHEMBL25923625 0.79 L3MBTL1 (0.50) L3MBTL1MEN1MAPTKMT2AIDO1
SCHEMBL22548069 0.78 IDO1 (0.47) KMT2AIDO1PPARGPPARAMAOB
SCHEMBL10862647 0.76 IDO1 (0.52) L3MBTL1MEN1MAPTKMT2AIDO1
SCHEMBL14099925 0.74 CCR5 (0.41) L3MBTL1MEN1MAPTKMT2AIDO1
SCHEMBL17215934 0.73 IDO1 (0.44) L3MBTL1MEN1MAPTKMT2AIDO1
SCHEMBL17215936 0.73 IDO1 (0.44) L3MBTL1MEN1MAPTKMT2AIDO1
SCHEMBL25872680 0.72 L3MBTL1 (0.54) L3MBTL1MEN1MAPTKMT2AIDO1
SCHEMBL21652288 0.71 L3MBTL1 (0.50) L3MBTL1MEN1MAPTKMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11219214-B2 Benzosultams and analogues and their use as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2022-01-11 US disclosed
US-20200323211-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-10-15 US disclosed
US-10736321-B2 Benzosultams and analogues and their use as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200323211-A1 BENZOSULTAMS AND ANALOGUES AND THEIR USE AS FUNGICIDES GABBR1, DPM1, CYP51A1 L3MBTL1 845/4885MEN1 3356/4885MAPT 1384/4885
US-10736321-B2 Benzosultams and analogues and their use as fungicides GABBR1, DPM1, CYP51A1 L3MBTL1 845/4885MEN1 3356/4885MAPT 1384/4885
US-11219214-B2 Benzosultams and analogues and their use as fungicides GABBR1, DPM1, CYP51A1 L3MBTL1 845/4885MEN1 3356/4885MAPT 1384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.