Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18510248 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL18130396 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL18511095 | 0.85 | DRD2 (0.42) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL12845912 | 0.80 | AHR (0.47) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL12045263 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL1685392 | 0.79 | AHR (0.50) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL30435112 | 0.79 | AHR (0.50) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL399327 | 0.79 | AHR (0.50) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL7029004 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTAHRHPGD | |
| SCHEMBL31501791 | 0.78 | AHR (0.44) | KDM4EALDH1A1MAPTAHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978753-B1 | NOVEL VIRAL REPLICATION INHIBITORS | UNIV LEUVEN KATH (BE) | 2020-08-12 | — | — | EP | disclosed |