Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386113 | 0.84 | MAPT (0.36) | ALDH1A1MAPTHPGDRGS12KDM4E | |
| SCHEMBL42875 | 0.84 | MAPT (0.36) | ALDH1A1MAPTHPGDRGS12KDM4E | |
| SCHEMBL24478175 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDRGS12KDM4E | |
| SCHEMBL29267318 | 0.77 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDRGS12KDM4E | |
| SCHEMBL17161322 | 0.76 | RGS12 (0.31) | ALDH1A1MAPTHPGDRGS12 | |
| SCHEMBL322165 | 0.74 | MAPT (0.40) | ALDH1A1MAPTHPGDRGS12KDM4E | |
| SCHEMBL15544952 | 0.73 | POLB (0.51) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL21180804 | 0.73 | KMT2A (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL16254246 | 0.72 | EHMT2 (0.42) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL14168948 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305784-B1 | HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-12 | — | — | EP | disclosed |