SCHEMBL22329973

SCHEMBL22329973

CC1(C)OB(c2ccc3c(c2)oc2c(-c4cccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)cccc23)OC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 5/20 0.41
LPL P06858 4/20 0.41
CSF1R P07333 1/20 0.39
ALOX5 P09917 2/20 0.38
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
PRKDC P78527 2/20 0.34
GGPS1 O95749 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
P4HB P07237 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31
TSHR P16473 2/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
EGFR P00533 1/20 0.31
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22195733 0.94 LIPG (0.43) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL22195848 0.92 LIPG (0.41) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL22113824 0.89 LIPG (0.38) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL20259765 0.89 LIPG (0.49) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL18090451 0.88 LIPG (0.49) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL21926220 0.87 LIPG (0.40) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL21926207 0.87 LIPG (0.40) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL25073616 0.87 LIPG (0.54) LIPGLPLCSF1RALOX5PRMT5
SCHEMBL22294956 0.86 LIPG (0.50) LIPGLPLALOX5GGPS1P4HB
SCHEMBL22135386 0.86 ALOX5 (0.50) LIPGLPLCSF1RALOX5PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581494-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-02-14 US disclosed
US-20200259098-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-08-13 US disclosed