SCHEMBL2233012

SCHEMBL2233012

C1CCN(C2CCNCC2)C1.[LiH]

nearest known ligand 0.86

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.52
L3MBTL3 Q96JM7 9/20 0.46
L3MBTL1 Q9Y468 8/20 0.46
MBTD1 Q05BQ5 5/20 0.38
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HRH3 Q9Y5N1 2/20 0.36
TP53BP1 Q12888 1/20 0.35
L3MBTL4 Q8NA19 1/20 0.35
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6395460 0.97 HTR6 (0.54) HTR6L3MBTL3L3MBTL1MBTD1HPGD
SCHEMBL51727 0.97 HTR6 (0.54) HTR6L3MBTL3L3MBTL1MBTD1HPGD
SCHEMBL3159634 0.95 HTR6 (0.52) HTR6L3MBTL3L3MBTL1MBTD1HPGD
Ammonia Solution, Strong SCHEMBL19410104 0.95 HTR6 (0.52) HTR6L3MBTL3L3MBTL1MBTD1HPGD
[1,4']Bipiperidinyl SCHEMBL42685 0.95 HTR6 (0.52) HTR6L3MBTL3L3MBTL1MBTD1HPGD
Hydrochloric Acid SCHEMBL15232249 0.95 HTR6 (0.52) HTR6L3MBTL3L3MBTL1MBTD1HPGD
[1,4']Bipiperidinyl SCHEMBL352141 0.95 HTR6 (0.52) HTR6L3MBTL3L3MBTL1MBTD1HPGD
Hydrochloric Acid SCHEMBL6952706 0.95 HTR6 (0.52) HTR6L3MBTL3L3MBTL1MBTD1HPGD
Hydrochloric Acid SCHEMBL5322658 0.92 HTR6 (0.50) HTR6L3MBTL3L3MBTL1MBTD1HPGD
[1,4']Bipiperidinyl SCHEMBL19410113 0.92 HTR6 (0.50) HTR6L3MBTL3L3MBTL1MBTD1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2193150-B1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORP (JP) 2020-09-23 EP disclosed
CN-103102436-B Liquid polymers and the synthesis of functionalized polymeric 株式会社普利司通 2016-08-03 CN disclosed
CN-103102436-A Synthesis of a liquid polymer and a functionalized polymer BRIDGESTONE CORP 2013-05-15 CN disclosed
CN-101821297-B Synthesis of liquid polymers and functionalized polymers BRIDGESTONE CORP 2013-02-13 CN disclosed
US-7981990-B2 Synthesis of a liquid polymer and a functionalized polymer BRIDGESTONE CORPORATION (JP) 2011-07-19 US disclosed
CN-101821297-A Synthesis of liquid polymers and functionalized polymers BRIDGESTONE CORP 2010-09-01 CN disclosed
EP-2193150-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER Bridgestone Corporation (JP) 2010-06-09 EP disclosed
WO-2009032154-A2 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-12 WO disclosed
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER BRIDGESTONE CORPORATION (JP) 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062451-A1 SYNTHESIS OF A LIQUID POLYMER AND A FUNCTIONALIZED POLYMER FGB, FIP1L1, PUF60 HTR6 3710/4885L3MBTL3 1342/4885L3MBTL1 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.