SCHEMBL22330160

SCHEMBL22330160

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4oc4ccc(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)cc45)cc3)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
MAPT P10636 5/20 0.47
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 4/20 0.47
HPGD P15428 4/20 0.47
ALOX5 P09917 2/20 0.45
KDM4E B2RXH2 3/20 0.45
LMNA P02545 2/20 0.45
GLA P06280 1/20 0.45
NTSR1 P30989 1/20 0.43
PTPRF P10586 6/20 0.40
PTPN2 P17706 6/20 0.40
PTPN1 P18031 6/20 0.40
MAPK1 P28482 1/20 0.38
POLB P06746 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
PIM1 P11309 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22330157 0.97 KMT2A (0.47) KMT2AMAPTALDH1A1MEN1HPGD
SCHEMBL22329532 0.97 KMT2A (0.47) KMT2AMAPTALDH1A1MEN1HPGD
SCHEMBL22329862 0.96 ALOX5 (0.47) KMT2AMAPTALDH1A1MEN1HPGD
SCHEMBL22329861 0.96 KMT2A (0.46) KMT2AMAPTALDH1A1MEN1HPGD
SCHEMBL22330159 0.95 KMT2A (0.48) KMT2AMAPTALDH1A1MEN1HPGD
SCHEMBL22329863 0.95 ALOX5 (0.49) MAPTALDH1A1HPGDALOX5KDM4E
SCHEMBL17425607 0.95 ALOX5 (0.49) MAPTALDH1A1HPGDALOX5KDM4E
SCHEMBL22883912 0.95 ALOX5 (0.49) MAPTALDH1A1HPGDALOX5KDM4E
SCHEMBL22330138 0.94 KMT2A (0.43) KMT2AMAPTALDH1A1MEN1HPGD
SCHEMBL20706100 0.94 ALOX5 (0.48) KMT2AMAPTALDH1A1MEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581494-B2 Organic light emitting device LG CHEM, LTD. (KR) 2023-02-14 US disclosed
US-20200259098-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-08-13 US disclosed