Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19171675 | 0.79 | JAK2 (0.33) | — | |
| SCHEMBL21706400 | 0.79 | SSTR4 (0.35) | SSTR4DRD4DRD3LMNAHTT | |
| SCHEMBL21706601 | 0.76 | SSTR4 (0.34) | SSTR4DRD4DRD3LMNAHTT | |
| SCHEMBL21451299 | 0.71 | SSTR4 (0.44) | SSTR4DRD4DRD3DYRK1AHTT | |
| SCHEMBL9607549 | 0.70 | SSTR4 (0.48) | SSTR4DRD4DRD3DYRK1ALMNA | |
| SCHEMBL20043180 | 0.69 | KDM4E (0.46) | HTT | |
| SCHEMBL23638563 | 0.68 | SSTR4 (0.34) | SSTR4DRD4DRD3 | |
| SCHEMBL26525736 | 0.65 | EGFR (0.31) | EGFR | |
| SCHEMBL16256035 | 0.65 | SSTR4 (0.46) | SSTR4DRD4DRD3DYRK1ALMNA | |
| SCHEMBL17849508 | 0.65 | SSTR4 (0.46) | SSTR4DRD4DRD3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142526-B2 | Spirocycle compounds and methods of making and using same | H. LUNDBECK A/S (DK) | 2021-10-12 | — | — | US | disclosed |
| US-20200255427-A1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255427-A1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | OPRL1, MGLL, OPRK1 | SSTR4 4198/4885DRD4 3561/4885DRD3 2758/4885 |
| US-11142526-B2 | Spirocycle compounds and methods of making and using same | OPRL1, MGLL, OPRK1 | SSTR4 4198/4885DRD4 3561/4885DRD3 2758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.