Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.51 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.51 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 3/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22330370 | 0.84 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL18103110 | 0.84 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL8348737 | 0.78 | CACNA2D1 (0.49) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL22330427 | 0.75 | CAPN1 (0.40) | KMT2A | |
| SCHEMBL2013100 | 0.74 | KMT2A (0.57) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL18100237 | 0.73 | CACNA2D1 (0.42) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL14060326 | 0.73 | CNR1 (0.56) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL14060328 | 0.73 | CNR1 (0.56) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL14060325 | 0.73 | CNR1 (0.56) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL18078097 | 0.73 | CACNA2D1 (0.46) | CACNA2D1CACNA1CCACNB3PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265074-B1 | PREGABALIN IMMUNOASSAYS | ARK DIAGNOSTICS INC (US) | 2020-08-12 | — | — | EP | disclosed |