Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16307668 | 0.83 | SMN1; SMN2 (0.49) | ADRA1AOPRM1OPRD1OPRK1AKT1 | |
| SCHEMBL24164344 | 0.80 | NAMPT (0.37) | OPRM1OPRD1OPRK1AKT1SMN1; SMN2 | |
| SCHEMBL18078100 | 0.79 | AKT1 (0.48) | OPRM1OPRD1OPRK1AKT1KMT2A | |
| SCHEMBL13093320 | 0.75 | MGLL (0.43) | OPRM1OPRD1OPRK1AKT1TP53 | |
| SCHEMBL19116362 | 0.75 | ALDH1A1 (0.43) | OPRM1OPRD1OPRK1AKT1SMN1; SMN2 | |
| SCHEMBL15892775 | 0.73 | HPGD (0.40) | OPRM1OPRD1OPRK1AKT1TP53 | |
| SCHEMBL18103110 | 0.73 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL22330370 | 0.73 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL22330429 | 0.73 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL17860045 | 0.72 | PTGS1 (0.42) | OPRM1OPRD1OPRK1AKT1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160266153-A1 | IMMUNOASSAY FOR PREGABALIN | RANDOX LABORATORIES LIMITED (GB) | 2016-09-15 | — | — | US | disclosed |
| EP-3067700-A1 | IMMUNOASSAY FOR PREGABALIN | Randox Laboratories Ltd. (GB) | 2016-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160266153-A1 | IMMUNOASSAY FOR PREGABALIN | GABRG1, GABRG3, GABRG2 | CACNA2D1 84/4885CACNA1C 106/4885CACNB3 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.