Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505848 | 0.79 | SMN1; SMN2 (0.52) | TP53SMN1; SMN2PSMB5ALDH1A1KMT2A | |
| SCHEMBL25574095 | 0.78 | CA1 (0.41) | TP53SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL13003356 | 0.77 | GNAI3 (0.44) | ALDH1A1 | |
| SCHEMBL24164337 | 0.76 | CACNA2D1 (0.42) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL18103106 | 0.75 | AAK1 (0.42) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL9795280 | 0.74 | ALDH1A1 (0.47) | TP53SMN1; SMN2PSMB5ALDH1A1KMT2A | |
| SCHEMBL22330429 | 0.73 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL22330370 | 0.73 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL18103110 | 0.73 | CACNA2D1 (0.51) | CACNA2D1CACNA1CCACNB3PGRADRA1A | |
| SCHEMBL21888407 | 0.72 | GABRR1 (0.50) | TP53SMN1; SMN2ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11703514-B2 | Pregabalin immunoassays | ARK DIAGNOSTICS, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20160282370-A1 | PREGABALIN IMMUNOASSAYS | ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160282370-A1 | PREGABALIN IMMUNOASSAYS | GABRG3, GABRG1, GABRB2 | CACNA2D1 107/4885CACNA1C 168/4885CACNB3 46/4885 |
| US-11703514-B2 | Pregabalin immunoassays | GABRG3, GABRG1, GABRB2 | CACNA2D1 107/4885CACNA1C 168/4885CACNB3 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.