Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090568 | 0.93 | GAA (0.63) | GAAGPR139SPHK2SMN1; SMN2KDM4E | |
| SCHEMBL7293621 | 0.85 | KDM4E (0.59) | GAAGPR139MEN1KMT2AMMP1 | |
| SCHEMBL7515133 | 0.85 | KDM4E (0.59) | GAAGPR139MEN1KMT2AMMP1 | |
| SCHEMBL23968027 | 0.82 | GPR139 (0.58) | GAAGPR139MEN1KMT2AMMP1 | |
| SCHEMBL7674509 | 0.81 | GAA (0.59) | GAAGPR139MEN1KMT2AMMP1 | |
| Hippuric Acid SCHEMBL28770427 | 0.79 | KDM4E (0.67) | GAAGPR139SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7412271 | 0.79 | MMP1 (0.73) | GAAGPR139MMP1SLC6A9SLC6A5 | |
| Hippuric Acid SCHEMBL27404536 | 0.79 | KDM4E (0.67) | GAAGPR139SMN1; SMN2KDM4EMAPT | |
| SCHEMBL10938763 | 0.79 | GAA (0.52) | GAAGPR139MEN1KMT2AMMP1 | |
| SCHEMBL27419582 | 0.79 | GPR139 (0.55) | GAAGPR139MEN1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523316-B1 | MELANOCORTIN-1-RECEPTOR AGONISTS | DSM IP ASSETS BV (NL) | 2021-11-03 | — | — | EP | disclosed |
| EP-3692978-A1 | NOVEL METHOD | DSM IP Assets B.V. (NL) | 2020-08-12 | — | — | EP | disclosed |