Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18674661 | 0.95 | RAB9A (0.64) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL11064658 | 0.82 | RAB9A (0.71) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL18674671 | 0.81 | AR (0.97) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL18674670 | 0.81 | AR (0.84) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL3004754 | 0.80 | SMN1; SMN2 (1.00) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL17266249 | 0.80 | SMN1; SMN2 (1.00) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL3761593 | 0.79 | RAB9A (0.74) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL17266248 | 0.78 | RAB9A (0.65) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL18674602 | 0.77 | RAB9A (0.75) | ARSMN1; SMN2HSD17B10TP53ALOX15 | |
| SCHEMBL3081074 | 0.76 | CNR2 (0.69) | ARSMN1; SMN2HSD17B10TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | disclosed |