Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | AR | P10275 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761593 | 0.89 | RAB9A (0.74) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL2557601 | 0.87 | SMN1; SMN2 (0.70) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL18674602 | 0.86 | RAB9A (0.75) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL18674661 | 0.86 | RAB9A (0.64) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL18674670 | 0.85 | AR (0.84) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11071836 | 0.83 | RAB9A (1.00) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL11075592 | 0.83 | RAB9A (0.70) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL17266248 | 0.82 | RAB9A (0.65) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL22334841 | 0.82 | AR (0.65) | RAB9ANPC1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL12291571 | 0.82 | SMN1; SMN2 (0.78) | RAB9ANPC1SMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56127364-A | — | — | None | — | — | JP | disclosed |
| US-9993409-B2 | Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler | L'OREAL (FR) | 2018-06-12 | — | — | US | disclosed |
| US-9993409-B2 | Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler | L'OREAL (FR) | 2018-06-12 | — | — | US | disclosed |
| US-20170087075-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | L'OREAL (FR) | 2017-03-30 | — | — | US | disclosed |
| US-20170087075-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | L'OREAL (FR) | 2017-03-30 | — | — | US | disclosed |
| US-4476128-A | ANTIARTHRITIC AGENTS ANTIBODY INHIBITORS | MITSUITOATSU CHEMICALS, INC. (JP) | 1984-10-09 | — | — | US | disclosed |
| JP-S56127364-A | NOVEL PIPERAZINE COMPOUND, ITS PREPARATION AND UTILIZATION | MITSUI TOATSU CHEM INC | 1981-10-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087075-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | KRT18, F12, CBR3 | RAB9A 3590/4885NPC1 4834/4885ALDH1A1 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.