⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14673188 | 1.00 | — | — | |
| SCHEMBL14673523 | 1.00 | — | — | |
| SCHEMBL5052804 | 1.00 | — | — | |
| SCHEMBL14673549 | 0.97 | — | — | |
| SCHEMBL2703024 | 0.90 | — | — | |
| SCHEMBL12614042 | 0.87 | ALDH1A1 (0.35) | — | |
| SCHEMBL9529889 | 0.86 | ALDH1A1 (0.31) | — | |
| SCHEMBL16152164 | 0.84 | ALDH1A1 (0.31) | — | |
| SCHEMBL12924149 | 0.81 | ALDH1A1 (0.42) | — | |
| SCHEMBL1788508 | 0.80 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536690-B1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | UNIV ARIZONA (US) | 2018-08-08 | — | — | EP | disclosed |
| US-8952025-B2 | Multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Ari (US) | 2013-10-10 | — | — | US | disclosed |
| EP-2536690-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | Arizona Board Of Regents (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103536-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | ARIZONA BOARD OF REGENTS (US) | 2011-08-25 | — | — | WO | disclosed |