Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17392756 | 1.00 | MEN1 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL12608306 | 1.00 | MEN1 (0.38) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL10976798 | 0.97 | MEN1 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6545066 | 0.97 | MEN1 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6409925 | 0.97 | MEN1 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9529889 | 0.91 | ALDH1A1 (0.31) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL23512039 | 0.90 | CYP3A4 (0.34) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL1841223 | 0.90 | — | — | |
| SCHEMBL19344722 | 0.89 | BLM (0.32) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL12754636 | 0.87 | MEN1 (0.46) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772540-B2 | Thermal responsive molecule | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20110124916-A1 | THERMAL RESPONSIVE MOLECULE | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2011-05-26 | — | — | US | disclosed |
| US-6699954-B2 | FOR FORMING THIN LAYER BEING SANDWICHED BETWEEN TWO ELECTRODES; ELECTROLUMINESCENT DIODE (LED) | UNIVERSITE JOSEPH FOURIER (FR) | 2004-03-02 | — | — | US | disclosed |
| US-20020099157-A1 | Monomers, polymers incorporating said monomers and their use in organic electroluminescent devices | UNIVERSITY JOSEPH FOURIER (FR) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124916-A1 | THERMAL RESPONSIVE MOLECULE | HEATR1, HEATR6, HSPH1 | MEN1 3476/4885THRB 863/4885HTT 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.