SCHEMBL2233507

SCHEMBL2233507

CC(=O)COC(=O)CC(O)(CC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
KDM4E B2RXH2 5/20 0.36
LMNA P02545 4/20 0.36
TSHR P16473 2/20 0.36
MAPT P10636 2/20 0.36
ALOX15 P16050 1/20 0.36
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
SLC13A5 Q86YT5 10/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
SLC13A2 Q13183 1/20 0.31
SLC13A3 Q8WWT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL591543 0.86 ALDH1A1 (0.62) ALDH1A1KDM4ELMNATSHRMAPT
Water SCHEMBL27884876 0.85 ALDH1A1 (0.60) ALDH1A1KDM4ELMNATSHRMAPT
Ammonia Solution, Strong SCHEMBL27983631 0.85 ALDH1A1 (0.60) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL9763262 0.84 ALDH1A1 (0.50) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL21314251 0.83 ALDH1A1 (0.58) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL27675923 0.83 ALDH1A1 (0.48) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL9829329 0.82 ALDH1A1 (0.52) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL5551171 0.82 ALDH1A1 (0.52) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL6001598 0.82 ALDH1A1 (0.47) ALDH1A1KDM4ELMNATSHRMAPT
SCHEMBL14674827 0.81 ALDH1A1 (0.56) ALDH1A1KDM4ELMNATSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100379792-C Process for manufacture of functionalized polyphenylene ethers GEN ELECTRIC (US) 2008-04-09 CN claimed
EP-3351621-B1 REGENERATED HAIR FOLLICLE PRIMORDIUM AGGREGATION MANUFACTURING METHOD, HAIR FOLLICLE TISSUE-CONTAINING SHEET, AND METHOD FOR MANUFACTURING HAIR FOLLICLE TISSUE-CONTAINING SHEET NAT UNIV CORP YOKOHAMA NAT UNIV (JP) 2023-11-22 EP disclosed
US-10865373-B2 Regenerated hair follicle primordium aggregation manufacturing method, hair follicle tissue-containing sheet, and method for manufacturing hair follicle tissue-containing sheet National University Corporation Yokohama National University (JP) 2020-12-15 US disclosed
CN-110536920-A Citric acid ester plasticizer and resin composition containing same LG CHEMICAL LTD 2019-12-03 CN disclosed
CN-110073222-A Methods, systems, and solid compositions for agent delivery 文塔纳医疗系统公司 2019-07-30 CN disclosed
EP-3351621-A1 REGENERATED HAIR FOLLICLE PRIMORDIUM AGGREGATION MANUFACTURING METHOD, HAIR FOLLICLE TISSUE-CONTAINING SHEET, AND METHOD FOR MANUFACTURING HAIR FOLLICLE TISSUE-CONTAINING SHEET National University Corporation Yokohama National University (JP) 2018-07-25 EP disclosed
CN-104650580-B Fire-retardant thermoplastic resin composite and its products formed 旭化成株式会社 2018-05-08 CN disclosed
CN-107847439-A Glucopyranosyl lipid A and allergen formulations for sublingual administration 赛诺菲 2018-03-27 CN disclosed
CN-107753428-A Adapalene vesica and its preparation and preparation method 北京盈科瑞创新医药股份有限公司 2018-03-06 CN disclosed
CN-107108559-A Crystalline forms of 5-chloro-N4- [2- (dimethylphosphoryl) phenyl ] -N2- { 2-methoxy-4- [4- (4-methylpiperazin-1-yl) piperidin-1-yl ] pyrimidine-2, 4-diamine 阿瑞雅德制药公司 2017-08-29 CN disclosed
CN-1131282-C Method for improving appearance quality of compatilized poly phenylene oxide-polyamide resin blend GEN ELECTRIC (US) 2003-12-17 CN disclosed
CN-1427872-A Reduction of carbonized particles in poly (arylene ether)-polyamide composition GEN ELECTRIC (US) 2003-07-02 CN disclosed
CN-1392129-A Process for preparing hypericum perforatum extract UNIV ZHONGSHAN (CN) 2003-01-22 CN disclosed
CN-1068025-C Extrudable thermoplastic composition comprising a compatibilized polyphenylene ether polyamide resin blend GEN ELECTRIC (US) 2001-07-04 CN disclosed
CN-1234416-A Method for improving appearance quality of compatilized poly phenylene oxide-polyamide resin blend GEN ELECTRIC (US) 1999-11-10 CN disclosed
CN-1231307-A Curable polyphenylene ether-thermosetting resin composition and process GEN ELECTRIC (US) 1999-10-13 CN disclosed
CN-1138065-A Flame retarded compositions of poly (phenylene ether), poly(arylene sulfide) and siloxane copolymer roxane CO GEN ELECTRIC (US) 1996-12-18 CN disclosed
CN-1135502-A Composition containing polyser, poly (arylidene thio-ether), paraplex and compatilizer compound GEN ELECTRIC (US) 1996-11-13 CN disclosed
CN-1126224-A Extrudable thermoplastic composition comprising a compatibilized polyphenylene ether polyamide resin blend GEN ELECTRIC (US) 1996-07-10 CN disclosed
CN-1106840-A Thermoplastic composition comprising a compatibilized polyphenylene etherpolyamide base resin, one or more phosphorus compounds GEN ELECTRIC (US) 1995-08-16 CN disclosed