Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 8/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613031 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNASLC15A2TSHR | |
| SCHEMBL7166799 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL426934 | 0.85 | ALDH1A1 (0.65) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL2233507 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL2861746 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL426065 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNATSHRMAPT | |
| Ethylene SCHEMBL10931218 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL426260 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL5570780 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNATSHRMAPT | |
| Ammonia Solution, Strong SCHEMBL21219115 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218714-B1 | SECO-STEROL COMPOUNDS EFFECTIVE IN INDUCING THE DIFFERENTIATION OF MALIGNANT CELLS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-08-07 | — | — | EP | disclosed |
| US-4940700-A | Seco-sterol compounds effective in inducing cell differentiation | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1990-07-10 | — | — | US | disclosed |
| US-4800198-A | ANTITUMOR | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1989-01-24 | — | — | US | disclosed |
| WO-1986006255-A1 | SECO-STEROL COMPOUNDS EFFECTIVE IN INDUCING THE DIFFERENTIATION OF MALIGNANT CELLS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1986-11-06 | — | — | WO | disclosed |