Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233635 | 1.00 | LMNA (0.40) | LMNAMAPTPPARGPPARAALDH1A1 | |
| SCHEMBL2183907 | 0.92 | MAPT (0.41) | LMNAMAPTPPARGALDH1A1HPGD | |
| SCHEMBL16496323 | 0.92 | MAPT (0.41) | LMNAMAPTPPARGALDH1A1HPGD | |
| SCHEMBL16496437 | 0.89 | THRA (0.43) | THRATHRB | |
| SCHEMBL2169676 | 0.89 | THRA (0.43) | THRATHRB | |
| SCHEMBL2827035 | 0.88 | TNFRSF1A (0.38) | LMNAMAPTALDH1A1HPGDPKM | |
| SCHEMBL2827033 | 0.88 | TNFRSF1A (0.38) | LMNAMAPTALDH1A1HPGDPKM | |
| SCHEMBL16496686 | 0.86 | MAPT (0.42) | LMNAMAPTPPARGALDH1A1HPGD | |
| SCHEMBL2169903 | 0.86 | MAPT (0.42) | LMNAMAPTPPARGALDH1A1HPGD | |
| SCHEMBL16495869 | 0.82 | LMNA (0.42) | LMNAMAPTPPARGALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346814-A2 | THYROID RECEPTOR LIGANDS | Cadila Healthcare Limited (IN) | 2011-07-27 | — | — | EP | claimed |