SCHEMBL22336532

SCHEMBL22336532

CC(=O)NC1C(CO)OC(CO)C(C)C[C@@H]1C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.39
▸ THRB P10828 1/20 0.39
▸ MAPK1 P28482 2/20 0.38
▸ CD69 Q07108 1/20 0.36
▸ OGA O60502 2/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ ASGR1 P07306 1/20 0.33
▸ LGALS8 O00214 1/20 0.32
▸ LGALS3 P17931 1/20 0.32
▸ LGALS4 P56470 1/20 0.32
▸ GAA P10253 1/20 0.31
▸ PYGB P11216 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13655844 0.78 ALDH1A1 (0.31) ALDH1A1LGALS8LGALS3
SCHEMBL17117587 0.77 OGA (0.38) ALDH1A1THRBMAPK1CD69OGA
SCHEMBL12936319 0.74 ALDH1A1 (0.58) ALDH1A1THRBMAPK1CD69OGA
SCHEMBL17771655 0.74 ALDH1A1 (0.58) ALDH1A1THRBMAPK1CD69OGA
SCHEMBL21452946 0.73 ATM (0.39) ALDH1A1SMN1; SMN2ASGR1
SCHEMBL14507147 0.72 MAPK1 (0.43) ALDH1A1THRBMAPK1CD69OGA
SCHEMBL14507155 0.72 ALDH1A1 (0.41) ALDH1A1THRBMAPK1CD69OGA
SCHEMBL22919274 0.71 ALDH1A1 (0.49) ALDH1A1THRBMAPK1CD69OGA
SCHEMBL7154123 0.70 MAPK1 (0.54) ALDH1A1THRBMAPK1CD69OGA
SCHEMBL14507148 0.70 ALDH1A1 (0.45) ALDH1A1THRBMAPK1CD69OGA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200254241-A1 ELECTRICAL METHOD OF DELIVERING HYALURONIC ACID THROUGH THE SKIN L'OREAL (FR) 2020-08-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200254241-A1 ELECTRICAL METHOD OF DELIVERING HYALURONIC ACID THROUGH THE SKIN CD44, CUTA, CD69 ALDH1A1 3798/4885THRB 2784/4885MAPK1 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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