SCHEMBL2233716

SCHEMBL2233716

CO[C@H]1O[C@H](C)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
M6PR P20645 2/20 0.44
MGAM O43451 4/20 0.40
SI P14410 4/20 0.40
G6PD P11413 2/20 0.38
FUCA1 P04066 1/20 0.38
AMY1A P0DUB6 1/20 0.36
CA9 Q16790 2/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
SYNJ2 O15056 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12070982 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15215703 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15121661 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL2505909 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15273797 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL24605082 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL1832193 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL15273793 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL13509342 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1
SCHEMBL767128 1.00 M6PR (0.44) M6PRMGAMSIG6PDFUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013024905-A1 COMBINATION DRUG OF ANTIBODY AGAINST LIPOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA AND ANTIBACTERIAL AGENT MEIJI SEIKA PHARMA CO., LTD. (JP) 2013-02-21 WO disclosed
WO-2013024905-A1 COMBINATION DRUG OF ANTIBODY AGAINST LIPOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA AND ANTIBACTERIAL AGENT MEIJI SEIKA PHARMA CO., LTD. (JP) 2013-02-21 WO disclosed
WO-2011102552-A1 ANTIBODY AGAINST A BAND LIPOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA MEIJI SEIKA KAISHA, LTD. (JP) 2011-08-25 WO disclosed
US-20070042030-A1 Preparation for the application of agents in mini-droplets IDEA AG (DE) 2007-02-22 US disclosed
US-7018824-B2 Mannosyl transfer with regeneration of GDP-mannose THE SCRIPPS RESEARCH INSTITUTE (US) 2006-03-28 US disclosed
US-20050221447-A1 water soluble transferase enzyme polypeptides, coded by exogenous DNA; glycosylation THE SCRIPPS RESEARCH INSTITUTE 2005-10-06 US disclosed
US-6919440-B2 Mannosyl transfer with regeneration of GDP-mannose THE SCRIPPS RESEARCH INSTITUTE (US) 2005-07-19 US disclosed
EP-0475160-B2 Preparation for drug application in minute droplet form IDEA AG (DE) 2004-07-14 EP disclosed
US-20030119090-A1 Mannosyl transfer with regeneration of GDP-mannose WONG CHI-HUEY (US) 2003-06-26 US disclosed
US-6485930-B1 Mannosyl transfer with regeneration of GDP-mannose THE SCRIPPS RESEARCH INSTITUTE 2002-11-26 US disclosed
US-6165500-A Preparation for the application of agents in mini-droplets IDEA AG (DE) 2000-12-26 US disclosed
US-5783677-A FORMING INTERMEDIATES BY TREATING 6-DEOXY-A-L-MANNOPYRANOSYL BROMIDE AND 2,3,4-TRI-O-BENZOATE WITH DIMETHYLSULFOXIDE, A BASE, AND A SOLVENT PROCTER & GAMBLE PHARMACEUTICALS, INC. 1998-07-21 US disclosed
US-5721217-A 14-AMINOANDROSTANE COMPOUNDS AS INOTROPIC AGENT TREATING CONGESTIVE HEART FAILURE THE PROCTER & GAMBLE COMPANY (US) 1998-02-24 US disclosed
EP-0720616-A1 NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1996-07-10 EP disclosed
EP-0475160-B1 Preparation for drug application in minute droplet form IDEA AG (DE) 1996-02-14 EP disclosed
WO-1995008558-A1 NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1995-03-30 WO disclosed
EP-0475160-A1 Preparation for drug application in minute droplet form Cevc, Gregor, Prof. Dr. (DE) 1992-03-18 EP disclosed
WO-1992003122-A1 PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS CEVC GREGOR (DE) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042030-A1 Preparation for the application of agents in mini-droplets FABP4, NPC1L1, LIPA M6PR 2907/4885MGAM 165/4885SI 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.