Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22337651 | 0.99 | KCNH2 (0.48) | KCNH2ADRB1ADRB2ADRB3L3MBTL1 | |
| SCHEMBL22321566 | 0.92 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321562 | 0.92 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321620 | 0.92 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321570 | 0.92 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321545 | 0.92 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321546 | 0.92 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321554 | 0.90 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321557 | 0.90 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 | |
| SCHEMBL22321592 | 0.90 | KCNH2 (0.48) | KCNH2ADRB1ADRB2TLR8TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220482-B2 | Aminopyridinemethanol compounds and their use | UNIVERSITE AMIENS PICARDIE JULES VERNE (FR) | 2022-01-11 | — | — | US | disclosed |
| US-20200255379-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | UNIV AMIENS PICARDIE JULES VERNE (FR) | 2020-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220482-B2 | Aminopyridinemethanol compounds and their use | QDPR, PNMT, CYP3A43 | KCNH2 404/4885ADRB1 25/4885ADRB2 22/4885 |
| US-20200255379-A1 | NOVEL AMINOPYRIDINEMETHANOL COMPOUNDS AND THEIR USE | QDPR, PNMT, CYP3A43 | KCNH2 529/4885ADRB1 25/4885ADRB2 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.