Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GLS | O94925 | 6/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796071 | 0.79 | PDE5A (0.55) | RAB9ANPC1CA1CA2CA5A | |
| SCHEMBL29672808 | 0.77 | CA1 (0.56) | RAB9ANPC1CA1CA2CA5A | |
| SCHEMBL1032275 | 0.77 | SMN1; SMN2 (0.53) | RAB9ANPC1CA1CA2CA5A | |
| SCHEMBL29827327 | 0.77 | RAB9A (0.50) | RAB9ANPC1CA1CA2CA5A | |
| SCHEMBL11715209 | 0.77 | RAB9A (0.50) | RAB9ANPC1CA1CA2CA5A | |
| SCHEMBL24015947 | 0.77 | SMN1; SMN2 (0.53) | RAB9ANPC1CA1CA2CA5A | |
| SCHEMBL966286 | 0.77 | CA1 (0.56) | RAB9ANPC1CA1CA2CA5A | |
| Hydrochloric Acid SCHEMBL11689290 | 0.76 | CA1 (0.55) | RAB9ANPC1CA1CA2CA5A | |
| Potassium Ion SCHEMBL11394989 | 0.76 | CA1 (0.55) | RAB9ANPC1CA1CA2CA5A | |
| SCHEMBL12019256 | 0.75 | POLB (0.55) | RAB9ANPC1CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |