Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 16/20 | 0.64 |
| ▸ | PRCP | P42785 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PREP | P48147 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23485251 | 0.94 | FKBP1A (0.60) | FKBP1APRCPKDM4ELMNAPREP | |
| SCHEMBL9200383 | 0.92 | PRCP (0.61) | FKBP1APRCPKDM4ELMNAPREP | |
| SCHEMBL10380778 | 0.89 | PRCP (0.62) | FKBP1APRCPKDM4ELMNAPREP | |
| SCHEMBL29692931 | 0.89 | FKBP1A (0.64) | FKBP1APRCPKDM4ELMNAPREP | |
| SCHEMBL8280028 | 0.86 | FKBP1A (0.66) | FKBP1AKDM4ELMNAPREP | |
| SCHEMBL5764209 | 0.86 | FKBP1A (0.66) | FKBP1AKDM4ELMNAPREP | |
| SCHEMBL21241271 | 0.85 | FKBP1A (0.70) | FKBP1A | |
| SCHEMBL21241279 | 0.85 | FKBP1A (0.70) | FKBP1A | |
| SCHEMBL16272917 | 0.84 | FKBP1A (0.66) | FKBP1AKDM4ELMNAPREP | |
| SCHEMBL7326760 | 0.84 | FKBP1A (0.66) | FKBP1AKDM4ELMNAPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161675-A1 | ARGINASE INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2020-08-13 | — | — | WO | disclosed |