Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | HTR6 | P50406 | 18/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972712 | 0.91 | KCNH2 (0.52) | KCNH2HTR6CYP3A4CYP2D6 | |
| SCHEMBL2235402 | 0.88 | KCNH2 (0.75) | KCNH2HTR6CYP3A4CYP2D6DRD2 | |
| SCHEMBL1972394 | 0.86 | KCNH2 (0.62) | KCNH2HTR6CYP3A4CYP2D6DRD2 | |
| SCHEMBL1975061 | 0.83 | HTR6 (0.57) | KCNH2HTR6 | |
| Hydrochloric Acid SCHEMBL1988380 | 0.79 | HTR6 (0.48) | KCNH2HTR6CYP3A4CYP2D6 | |
| SCHEMBL1976784 | 0.79 | KCNH2 (0.62) | KCNH2HTR6CYP3A4CYP2D6DRD2 | |
| SCHEMBL1975081 | 0.78 | HTR6 (0.53) | KCNH2HTR6CYP3A4CYP2D6DRD2 | |
| SCHEMBL1975024 | 0.76 | CYP3A4 (0.59) | KCNH2HTR6CYP3A4CYP2D6DRD2 | |
| SCHEMBL1972909 | 0.75 | CYP3A4 (0.53) | KCNH2HTR6CYP3A4CYP2D6DRD2 | |
| Hydrochloric Acid SCHEMBL1975102 | 0.75 | HTR6 (0.58) | KCNH2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003670-B2 | Aminoalkoxy aryl sulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-08-23 | — | — | US | disclosed |
| US-20100087484-A1 | AMINOALKOXY ARYL SULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087484-A1 | AMINOALKOXY ARYL SULFONAMIDE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | HTR6, HTR5A, HTR1B | KCNH2 1408/4885HTR6 1/4885CYP3A4 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.