Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12484917 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LOXL2MEN1POLB | |
| SCHEMBL5685388 | 0.82 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1POLBHPGD | |
| SCHEMBL27453852 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1POLBHPGD | |
| SCHEMBL21936180 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LOXL2TDP1TSHRIDO1 | |
| SCHEMBL29951708 | 0.80 | KDM4E (0.57) | ALDH1A1HPGDKDM4EPTGS2RAB9A | |
| SCHEMBL28309278 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1POLBHPGD | |
| SCHEMBL14329424 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1POLBHPGD | |
| SCHEMBL30021567 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1POLBHPGD | |
| SCHEMBL21902929 | 0.77 | CA2 (0.41) | ALDH1A1SMN1; SMN2MEN1POLBHPGD | |
| SCHEMBL12319652 | 0.77 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MEN1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020161275-A1 | NEW N-BENZYL-2-PHENOXYBENZAMIDE DERIVATIVES AS PROSTAGLANDIN E2 (PGE2) RECEPTORS MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2020-08-13 | — | — | WO | disclosed |