Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22339516 | 0.81 | CA1 (0.36) | CA12CA1CA2CA14 | |
| SCHEMBL22339638 | 0.72 | SLC6A2 (0.32) | — | |
| SCHEMBL15039547 | 0.69 | CA2 (0.40) | CA12CA1CA2CA14HTR2C | |
| SCHEMBL20159946 | 0.69 | HTR2C (0.37) | CA12CA1CA2CA14HTR2C | |
| SCHEMBL24693471 | 0.67 | CYP1A2 (0.32) | — | |
| SCHEMBL18611360 | 0.67 | CRY1 (0.35) | CA12CA1CA2CA14 | |
| SCHEMBL4510179 | 0.66 | JAK2 (0.39) | HTR2CHTR2BNPY5RJAK2JAK1 | |
| SCHEMBL23775289 | 0.66 | CA1 (0.37) | CA12CA1CA2CA14 | |
| SCHEMBL14566158 | 0.66 | — | — | |
| SCHEMBL4783003 | 0.65 | CA1 (0.36) | CA12CA1CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020160707-A1 | ALKYLBORONIC ACIDS AS ARGINASE INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2020-08-13 | — | — | WO | disclosed |