Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22340274 | 1.00 | TDP2 (0.38) | TDP2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL22341027 | 1.00 | TDP2 (0.38) | TDP2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL22340318 | 0.82 | PDE10A (0.42) | TDP2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL22340999 | 0.82 | PDE10A (0.42) | TDP2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL21306205 | 0.71 | HRH2 (0.33) | TDP2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL909717 | 0.71 | CHRM3 (0.43) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6396181 | 0.70 | CHRM3 (0.43) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8687212 | 0.70 | CHRM3 (0.46) | TDP2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL909354 | 0.69 | PDE10A (0.64) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22340832 | 0.69 | GSK3A (0.35) | TDP2CHRM3PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163405-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2020-08-13 | — | — | WO | disclosed |