SCHEMBL2234098

SCHEMBL2234098

O=C(O)CCOc1ccc(C(=O)O)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.69
L3MBTL1 Q9Y468 2/20 0.67
MAPK1 P28482 2/20 0.61
TSHR P16473 2/20 0.61
TP53 P04637 1/20 0.61
PLA2G4B P0C869 2/20 0.59
ALDH1A1 P00352 1/20 0.59
MMP2 P08253 1/20 0.57
USP2 O75604 1/20 0.57
ALOX15 P16050 1/20 0.57
HSD17B10 Q99714 1/20 0.57
PPARA Q07869 1/20 0.57
RARB P10826 4/20 0.56
HTT P42858 1/20 0.56
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231223 0.90 PKM (0.67) PKML3MBTL1MAPK1TSHRTP53
SCHEMBL2230125 0.89 PPARA (0.73) PKML3MBTL1TSHRTP53PLA2G4B
SCHEMBL196110 0.87 PKM (0.88) PKML3MBTL1MAPK1TSHRTP53
SCHEMBL11589042 0.87 PPARA (0.71) PKML3MBTL1TSHRTP53PLA2G4B
SCHEMBL2255415 0.87 PPARA (0.71) PKML3MBTL1TSHRTP53PLA2G4B
SCHEMBL28279260 0.87 PPARA (0.71) PKML3MBTL1TSHRTP53PLA2G4B
SCHEMBL2233264 0.87 PPARA (0.71) PKML3MBTL1TSHRTP53PLA2G4B
Sebacic Acid SCHEMBL5050874 0.87 PLA2G4B (0.68) PKML3MBTL1MAPK1TSHRTP53
SCHEMBL8133488 0.87 PPARA (0.71) PKML3MBTL1TSHRTP53PLA2G4B
SCHEMBL21878643 0.86 PKM (0.67) PKML3MBTL1MAPK1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012036737-A3 RECEIVER FILL VALVE AND CONTROL METHOD TRANE INTERNATIONAL INC. (US) 2012-05-10 WO disclosed
EP-1736512-B1 CONDUCTIVE RESIN COMPOSITION ASAHI KASEL CHEMICALS CORP (JP) 2011-12-14 EP disclosed
EP-1466724-B1 Thermoplastic resin composition and multi-layer laminate MITSUBISHI CHEM CORP (JP) 2011-12-07 EP disclosed
US-7977432-B2 Comprising at least two polymer end blocks and at least one saturated polymer interior block wherein each end block is resistant to lithiation and at least one interior block is susceptible to lithiation; for semi-permeable membrane with high water transport properties that maintains wet strength KRATON POLYMERS U.S. LLC (US) 2011-07-12 US disclosed
US-7696274-B2 Conductive resin composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-04-13 US disclosed
US-20080171828-A1 FUNCTIONALIZED BLOCK COPOLYMERS, METHOD FOR MAKING SAME, AND VARIOUS USES FOR SUCH BLOCK COPOLYMERS KRATON POLYMERS U.S. LLC. (US) 2008-07-17 US disclosed
US-20070205401-A1 Conductive Resin Composition ASAHI KASEL CHEMICALS CORPORATION (JP) 2007-09-06 US disclosed
EP-1277807-B1 Thermoplastic resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2007-05-02 EP disclosed
EP-1736512-A1 CONDUCTIVE RESIN COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2006-12-27 EP disclosed
US-7008991-B2 Thermoplastic resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2006-03-07 US disclosed
US-4107130-A SELECTIVELY HYDROGENATED ALKENYLARENE-DIENE BLOCK COPOLYMER, DISSIMILAR ENGINEERING THERMOPLASTIC RESIN SHELL OIL COMPANY (US) 1978-08-15 US disclosed
US-4102854-A Multicomponent polyolefin-block copolymer polycarbonate blends SHELL OIL COMPANY (US) 1978-07-25 US disclosed
US-4101605-A HYDROGENATED CONJUGATED DIENE-MONOALKENYL ARENE COPOLYMER SHELL OIL COMPANY (US) 1978-07-18 US disclosed
US-4090996-A IMPACT STRENGTH SHELL OIL COMPANY (US) 1978-05-23 US disclosed
US-4088627-A Multicomponent polyurethane-block copolymer blends SHELL OIL COMPANY (US) 1978-05-09 US disclosed
US-4088626-A Multicomponent polysulfone-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-05-09 US disclosed
US-4085163-A HYDROGENATED MONOALKENYL ARYL-DIENE BLOCK COPOLYMER SHELL OIL COMPANY (US) 1978-04-18 US disclosed
US-4081424-A OLEFIN COPOLYMERS/AROMATIC/, COPOLYENES/CONJUGATED/, THERMOPLASTIC RESIN SHELL OIL COMPANY (US) 1978-03-28 US disclosed
US-4080356-A Multicomponent polyacetal-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-03-21 US disclosed
US-4080357-A Multicomponent halogenated thermoplastic-block copolymer-polymer blends SHELL OIL COMPANY (US) 1978-03-21 US disclosed