Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27688895 | 0.82 | LMNA (0.52) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL1854910 | 0.80 | SLC6A2 (0.51) | LMNAPTGS1CYP2D6ADRB2ADRB1 | |
| SCHEMBL9497769 | 0.79 | LMNA (0.48) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL9229780 | 0.78 | LMNA (0.56) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL14954600 | 0.78 | LMNA (0.56) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL97377 | 0.78 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL13385106 | 0.78 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL9178337 | 0.78 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| SCHEMBL27864161 | 0.78 | LMNA (0.47) | LMNAMAOAPTGS1CYP2D6MTNR1A | |
| Ammonia Solution, Strong SCHEMBL28834669 | 0.76 | LMNA (0.65) | LMNAMAOAPTGS1CYP2D6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102603496-A | Method for synthesizing 1-butoxy-2,3-difluorobenzene | PANJIN XINGFU CHEMICAL CO LTD | 2012-07-25 | — | — | CN | claimed |
| US-9777216-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2017-10-03 | — | — | US | disclosed |
| CN-102753653-B | Liquid crystal media | 默克专利股份有限公司 | 2016-11-23 | — | — | CN | disclosed |
| EP-2534223-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-21 | — | — | EP | disclosed |
| EP-2534223-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2012-12-19 | — | — | EP | disclosed |
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| CN-102753653-A | Liquid crystalline medium | MERCK PATENT GMBH | 2012-10-24 | — | — | CN | disclosed |
| CN-102603496-A | Method for synthesizing 1-butoxy-2,3-difluorobenzene | PANJIN XINGFU CHEMICAL CO LTD | 2012-07-25 | — | — | CN | disclosed |
| WO-2011098224-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | WO | disclosed |
| CN-1966482-B | Preparation method of liquid crystal compound containing cyclohexyl and lateral o-difluoro-benzene | VALIANT FINE CHEMICALS CO LTD YANTAI | 2010-05-12 | — | — | CN | disclosed |
| CN-100584814-C | Method for preparing difluoro alkyl ether benzene | KANGPENG CHEMICAL CO LTD SHANGHAI | 2010-01-27 | — | — | CN | disclosed |
| CN-101003468-A | Method for preparing difluoro alkyl ether benzene | KANGPENG CHEMICAL CO LTD SHANG (CN) | 2007-07-25 | — | — | CN | disclosed |
| CN-1966482-A | Preparation method of cyclohexyl-containing lateral o-difluorobenzene liquid crystal compound | VALIANT FINE CHEMICALS CO LTD (CN) | 2007-05-23 | — | — | CN | disclosed |
| CN-1948251-A | Preparation method of 2,3-difluoro alkoxy benzene | SHANGHAI KANGPENG CHEMICAL CO (CN) | 2007-04-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | NEFM, VIM, PLG | LMNA 97/4885MAOA 1008/4885PTGS1 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.