Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SCN4A | P35499 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97377 | 1.00 | LMNA (0.68) | LMNAMAOAPTGS1MAPTPOLB | |
| Ammonia Solution, Strong SCHEMBL28834669 | 0.98 | LMNA (0.65) | LMNAMAOAPTGS1MAPTPOLB | |
| Ethylene Glycol SCHEMBL6560927 | 0.91 | LMNA (0.64) | LMNAMAOAPTGS1MAPTPOLB | |
| Ether SCHEMBL7051516 | 0.89 | LMNA (0.57) | LMNAMAOAPTGS1MAPTPOLB | |
| SCHEMBL10583987 | 0.88 | LMNA (0.55) | LMNAMAOAPTGS1MAPTPOLB | |
| Propylene Glycol SCHEMBL6558972 | 0.88 | LMNA (0.71) | LMNAMAOAPTGS1MAPTPOLB | |
| SCHEMBL123415 | 0.87 | MAPT (0.55) | LMNAMAOAPTGS1MAPTPOLB | |
| SCHEMBL14672093 | 0.87 | MAPT (0.57) | LMNAMAOAPTGS1MAPTPOLB | |
| SCHEMBL20385241 | 0.86 | LMNA (0.63) | LMNAMAOAPTGS1MAPTPOLB | |
| SCHEMBL13385106 | 0.85 | LMNA (0.68) | LMNAMAOAPTGS1SCN4AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |