Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391850 | 0.83 | RXRA (0.39) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL27262596 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1MCL1CYP1A2POLB | |
| SCHEMBL7865093 | 0.77 | MCL1 (0.37) | KDM4EALDH1A1MCL1NOTUMCYP1A2 | |
| SCHEMBL2235924 | 0.75 | ALDH1A1 (0.39) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL8391701 | 0.75 | NOTUM (0.43) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL27990317 | 0.75 | ALDH1A1 (0.50) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL23581891 | 0.74 | KDM4E (0.51) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL1579844 | 0.74 | NOTUM (0.41) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL8391483 | 0.72 | ALDH1A1 (0.36) | RXRARXRBKDM4EALDH1A1HPGD | |
| SCHEMBL2233514 | 0.72 | SOS1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536277-B1 | 3-AMINOCARBONYL SUBSTITUTED BENZOYLCYCLOHEXANDIONS AND THEIR APPLICATION AS HERBICIDES | BAYER IP GMBH (DE) | 2016-01-20 | — | — | EP | disclosed |
| CN-102781235-B | 3-aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | BAYER CROPSCIENCE AG | 2015-04-22 | — | — | CN | disclosed |
| US-8557741-B2 | 3-aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2013-10-15 | — | — | US | disclosed |
| EP-2536277-A1 | 3-AMINOCARBONYL-SUBSTITUTED BENZOYLCYCLOHEXANEDIONES AND THEIR USE AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011101321-A1 | 3-AMINOCARBONYL-SUBSTITUTED BENZOYLCYCLOHEXANEDIONES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-25 | — | — | WO | disclosed |
| US-20110207605-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-08-25 | — | — | US | disclosed |
| CN-1083688-C | New herbicides | RHONE POULENC AGRICULTURE (GB) | 2002-05-01 | — | — | CN | disclosed |
| US-5856274-A | 4-benzoyl isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0625508-B1 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0682659-B1 | 4-Benzoyl isoxazole derivatives, their preparation and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0682659-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES. | RHONE POULENC AGRICULTURE (GB) | 1995-11-22 | — | — | EP | disclosed |
| EP-0625508-A2 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1994018179-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD (GB) | 1994-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207605-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones and their use as herbicides | DDT, CBR3, CBR1 | RXRA 478/4885RXRB 352/4885KDM4E 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.