⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15063736 | 0.80 | BCL2L1 (0.35) | — | |
| SCHEMBL3518 | 0.71 | — | — | |
| SCHEMBL5584368 | 0.71 | — | — | |
| SCHEMBL1067623 | 0.69 | — | — | |
| SCHEMBL596912 | 0.69 | — | — | |
| SCHEMBL192055 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL4594834 | 0.67 | — | — | |
| SCHEMBL7498491 | 0.67 | — | — | |
| SCHEMBL27709 | 0.67 | — | — | |
| SCHEMBL69724 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 614 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239755-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-07-18 | — | — | US | claimed |
| CN-118063353-A | Chiral nitroxide compound and preparation method and application thereof | 贵州大学 | 2024-05-24 | — | — | CN | claimed |
| CN-112004813-B | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-110770214-B | Heterocyclic P2X7 antagonists | 布雷耶疗法有限公司 | 2024-03-29 | — | — | CN | claimed |
| EP-4330234-A1 | SUBSTITUTED PYRIDAZINONES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-03-06 | — | — | EP | claimed |
| CN-117222625-A | Substituted pyridazinones, salts or N-oxides thereof and their use as herbicidal agents | 拜耳公司 | 2023-12-12 | — | — | CN | claimed |
| US-11623919-B2 | Heterocyclic P2X7 antagonists | BREYE THERAPEUTICS APS (DK) | 2023-04-11 | — | — | US | claimed |
| CN-112004813-A | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2020-11-27 | — | — | CN | claimed |
| EP-3619200-A1 | HETEROCYCLIC P2X7 ANTAGONISTS | AXXAM S.p.A. (IT) | 2020-03-11 | — | — | EP | claimed |
| CN-110818598-A | Cathepsin inhibitor and preparation method and application thereof | 沈阳药科大学 | 2020-02-21 | — | — | CN | claimed |
| EP-1446392-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | Aventis Pharmaceuticals, Inc. (US) | 2004-08-18 | — | — | EP | claimed |
| US-20040116404-A1 | Sulphones which modulate the action of gamma secretase | MERCK SHARP & DOHME LTD. (GB) | 2004-06-17 | — | — | US | claimed |
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | AXYS PHARMACEUTICALS, INC. | 2004-01-22 | — | — | US | claimed |
| EP-1379498-A1 | SULPHONES WHICH MODULATE THE ACTION OF GAMMA SECRETASE | MERCK SHARP & DOHME LTD. (GB) | 2004-01-14 | — | — | EP | claimed |
| US-20030199506-A1 | Novel compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS INC. | 2003-10-23 | — | — | US | claimed |
| WO-2003042197-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-05-22 | — | — | WO | claimed |
| WO-2002081435-A1 | SULPHONES WHICH MODULATE THE ACTION OF GAMMA SECRETASE | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-17 | — | — | WO | claimed |
| EP-1212302-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-06-12 | — | — | EP | claimed |
| WO-2001019796-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| US-5767278-A | ANTICARCINOGENIC AGENTS | GERON CORPORATION (US) | 1998-06-16 | — | — | US | claimed |