⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455467 | 0.80 | TXN (0.36) | — | |
| SCHEMBL3713009 | 0.71 | — | — | |
| SCHEMBL5584028 | 0.71 | AHR (0.30) | — | |
| SCHEMBL38194 | 0.71 | — | — | |
| SCHEMBL3518 | 0.71 | — | — | |
| SCHEMBL5581408 | 0.69 | — | — | |
| SCHEMBL15063974 | 0.68 | TAAR1 (0.48) | — | |
| SCHEMBL5581454 | 0.67 | — | — | |
| SCHEMBL597388 | 0.67 | — | — | |
| SCHEMBL596641 | 0.67 | TRPV4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1896 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| EP-3702354-B1 | COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY AND USE THEREOF | HAIHE BIOPHARMA CO LTD (CN) | 2024-05-22 | — | — | EP | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| EP-3750894-B1 | UREA-SUBSTITUTED AROMATIC RING-LINKED DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2024-04-03 | — | — | EP | claimed |
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | claimed |
| EP-4330247-A1 | COMPOUNDS AND THEIR USES AS CD38 INHIBITORS | Nanjing Immunophage Biotech Co., Ltd (CN) | 2024-03-06 | — | — | EP | claimed |
| EP-3615527-B1 | NEW AZAQUINOLINE DERIVATIVES | ELANCO ANIMAL HEALTH GMBH (DE) | 2024-03-06 | — | — | EP | claimed |
| WO-2024017178-A1 | SUBSTITUTED HYDANTOIN COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | AVITAR BIOSCIENCES, INC. (CN) | 2024-01-25 | — | — | WO | claimed |
| US-20240000767-A1 | COMBINATION OF AN ALPHA2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONIST WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-04 | — | — | US | claimed |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| EP-1246790-A1 | SUBSTITUTED 1 AND 2 NAPHTHOL MANNICH BASES | Grünenthal GmbH (DE) | 2002-10-09 | — | — | EP | claimed |
| US-6436961-B1 | SUBSTANCE P RECEPTOR ANTAGONIST; 2-PHENYL-3-BENZYLAMINOPIPERIDINES | PFIZER INC | 2002-08-20 | — | — | US | claimed |
| WO-2001047885-A1 | SUBSTITUTED INDOLE MANNICH BASES | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-2001047866-A1 | SUBSTITUTED 1 AND 2 NAPHTHOL MANNICH BASES | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-2001047878-A1 | SUBSTITUTED PYRROLE MANNICH BASES TO COMBAT PAIN AND ALLERGIC REACTIONS | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-2001047882-A2 | SUBSTANCE LIBRARY WHICH CAN BE OBTAINED BY REACTING ALDEHYDES WITH SECONDARY AMINES, ACID CHLORIDES AND NAPHTHOL, PYRROLE AND/OR INDOLE COMPOUNDS | Grünenthal GmbH (DE) | 2001-07-05 | — | — | WO | claimed |
| CN-1250049-A | 2,5-substituting-1,3,4-oxadiazole compound and its preparation and application | UNIV EAST CHINA SCIENCE & ENG (CN) | 2000-04-12 | — | — | CN | claimed |
| CN-1216542-A | 1, 3-oxazin-4-one derivatives as herbicides, process and intermediates for their preparation | RHONE POULENC AGRICULTURE (GB) | 1999-05-12 | — | — | CN | claimed |
| US-4455307-A | Antihypertensive use of triazolobenzodiazepines | THE UPJOHN COMPANY (US) | 1984-06-19 | — | — | US | claimed |
| EP-0087850-A1 | Benzodiazepines for anti-hypertensive use | THE UPJOHN COMPANY (US) | 1983-09-07 | — | — | EP | claimed |