SCHEMBL22344786

SCHEMBL22344786

[CH2]CS(=O)(=O)CCN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40
SLC6A9 P48067 1/20 0.33
CYP1A2 P05177 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GLA P06280 1/20 0.31
TGM2 P21980 1/20 0.30
APEX1 P27695 1/20 0.30
S1PR1 P21453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22344784 1.00 HSD17B10 (0.40) HSD17B10SLC6A9CYP1A2MAPK1SMN1; SMN2
SCHEMBL23904651 0.84 HSD17B10 (0.41) HSD17B10SLC6A9CYP1A2MAPK1SMN1; SMN2
SCHEMBL22354643 0.81 HSD17B10 (0.39) HSD17B10SLC6A9CYP1A2APEX1S1PR1
SCHEMBL19016234 0.77 HSD17B10 (0.39) HSD17B10SLC6A9CYP1A2MAPK1SMN1; SMN2
SCHEMBL22354553 0.77 HSD17B10 (0.39) HSD17B10SLC6A9CYP1A2MAPK1SMN1; SMN2
SCHEMBL22354582 0.77 HSD17B10 (0.36) HSD17B10SLC6A9SMN1; SMN2APEX1S1PR1
SCHEMBL19016168 0.77 HSD17B10 (0.36) HSD17B10SLC6A9APEX1S1PR1
SCHEMBL26434198 0.77 HSD17B10 (0.36) HSD17B10SLC6A9APEX1S1PR1
SCHEMBL27780135 0.77 HRH3 (0.37) CYP1A2MAPK1SMN1; SMN2
SCHEMBL8742080 0.76 HSD17B10 (0.62) HSD17B10SLC6A9CYP1A2MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES ANTAROS MEDICAL AB (SE) 2023-04-27 US disclosed
CN-108697767-B Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes 安塔罗斯医疗公司 2022-04-15 CN disclosed
US-11046743-B2 Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes ANTAROS MEDICAL AB (SE) 2021-06-29 US disclosed
EP-3389697-B1 SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES ANTAROS MEDICAL AB (SE) 2020-12-16 EP disclosed
US-20200262885-A1 SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES ANTAROS MEDICAL AB (SE) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES GIPR, GRPR, GLP1R HSD17B10 4682/4885SLC6A9 934/4885CYP1A2 4878/4885
US-20200262885-A1 SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES GLP1R, GCGR, GIPR HSD17B10 4571/4885SLC6A9 914/4885CYP1A2 4798/4885
US-11046743-B2 Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes GLP1R, GCGR, GIPR HSD17B10 4571/4885SLC6A9 914/4885CYP1A2 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.