SCHEMBL23904651

SCHEMBL23904651

CCS(=O)(=O)CCN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.41
S1PR1 P21453 1/20 0.36
SLC6A9 P48067 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
CYP1A2 P05177 1/20 0.32
MAPK1 P28482 1/20 0.32
CACNA1H O95180 1/20 0.32
ALOX15 P16050 1/20 0.32
GLA P06280 1/20 0.32
APEX1 P27695 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22354643 0.89 HSD17B10 (0.39) HSD17B10S1PR1SLC6A9CYP1A2ALOX15
SCHEMBL22344784 0.84 HSD17B10 (0.40) HSD17B10S1PR1SLC6A9SMN1; SMN2CYP1A2
SCHEMBL22344786 0.84 HSD17B10 (0.40) HSD17B10S1PR1SLC6A9SMN1; SMN2CYP1A2
SCHEMBL22779191 0.82 SMN1; SMN2 (0.40) HSD17B10S1PR1SMN1; SMN2CYP1A2MAPK1
SCHEMBL26434198 0.82 HSD17B10 (0.36) HSD17B10S1PR1SLC6A9CACNA1HAPEX1
SCHEMBL19016168 0.82 HSD17B10 (0.36) HSD17B10S1PR1SLC6A9CACNA1HAPEX1
SCHEMBL22354582 0.82 HSD17B10 (0.36) HSD17B10S1PR1SLC6A9SMN1; SMN2APEX1
SCHEMBL10735957 0.81 CYP2C19 (0.34) SMN1; SMN2ALOX15
SCHEMBL18803169 0.78 PAOX (0.38) SMN1; SMN2SIGMAR1
SCHEMBL15499754 0.78 HSD17B10 (0.48) HSD17B10S1PR1SLC6A9SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES ANTAROS MEDICAL AB (SE) 2023-04-27 US disclosed
WO-2021198229-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES ANTAROS MEDICAL AB (SE) 2021-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES GIPR, GRPR, GLP1R HSD17B10 4682/4885S1PR1 460/4885SLC6A9 934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.