SCHEMBL22354582

SCHEMBL22354582

CC(C)CCS(=O)(=O)CCN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.36
SLC6A9 P48067 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PIK3CD O00329 1/20 0.31
TACR1 P25103 2/20 0.31
APEX1 P27695 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MCL1 Q07820 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
GCLC P48506 1/20 0.30
S1PR1 P21453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22354643 0.82 HSD17B10 (0.39) HSD17B10SLC6A9APEX1KDM4EALDH1A1
SCHEMBL23904651 0.82 HSD17B10 (0.41) HSD17B10SLC6A9SMN1; SMN2APEX1S1PR1
SCHEMBL15496587 0.81 HSD17B10 (0.44) HSD17B10SLC6A9TP53SMN1; SMN2PIK3CD
SCHEMBL26434198 0.78 HSD17B10 (0.36) HSD17B10SLC6A9APEX1S1PR1
SCHEMBL19016168 0.78 HSD17B10 (0.36) HSD17B10SLC6A9APEX1S1PR1
SCHEMBL22344786 0.77 HSD17B10 (0.40) HSD17B10SLC6A9SMN1; SMN2APEX1S1PR1
SCHEMBL22344784 0.77 HSD17B10 (0.40) HSD17B10SLC6A9SMN1; SMN2APEX1S1PR1
SCHEMBL22779191 0.76 SMN1; SMN2 (0.40) HSD17B10SMN1; SMN2KDM4EALDH1A1S1PR1
SCHEMBL10024737 0.74 HSD17B10 (0.44) HSD17B10SLC6A9TP53SMN1; SMN2TACR1
SCHEMBL8742080 0.71 HSD17B10 (0.62) HSD17B10SLC6A9SMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11046743-B2 Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes ANTAROS MEDICAL AB (SE) 2021-06-29 US disclosed
US-20200262885-A1 SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES ANTAROS MEDICAL AB (SE) 2020-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262885-A1 SELECTIVE GLUCAGON RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING PURPOSES GLP1R, GCGR, GIPR HSD17B10 4571/4885SLC6A9 914/4885TP53 3379/4885
US-11046743-B2 Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes GLP1R, GCGR, GIPR HSD17B10 4571/4885SLC6A9 914/4885TP53 3379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.