SCHEMBL22345127

SCHEMBL22345127

Cl[Pt]Cl.Nc1ccnc(-c2ccccn2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 2/20 0.56
KDM4E B2RXH2 8/20 0.52
LMNA P02545 4/20 0.52
CCR1 P32246 3/20 0.52
CCR5 P51681 3/20 0.52
CCR8 P51685 3/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
METAP1 P53582 1/20 0.52
BLM P54132 1/20 0.52
HIF1A Q16665 1/20 0.52
DOHH Q9BU89 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
KDM6B O15054 1/20 0.46
KDM4A O75164 1/20 0.46
KDM5C P41229 1/20 0.46
KDM4C Q9H3R0 1/20 0.46
KDM2A Q9Y2K7 1/20 0.46
KDM3A Q9Y4C1 1/20 0.46
TP53 P04637 6/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247730 0.92 ASIC3 (0.64) ASIC3KDM4ELMNACCR1CCR5
SCHEMBL30253423 0.92 ASIC3 (0.64) ASIC3KDM4ELMNACCR1CCR5
SCHEMBL5685444 0.85 KDM4E (0.67) ASIC3KDM4ELMNACCR1CCR5
Dipyridyl SCHEMBL1278984 0.82 KDM4E (0.78) KDM4ELMNACCR1CCR5CCR8
Sulfuric Acid SCHEMBL30536947 0.81 ASIC3 (0.51) ASIC3KDM4ELMNACCR1CCR5
Sulfuric Acid SCHEMBL30536905 0.81 ASIC3 (0.51) ASIC3KDM4ELMNACCR1CCR5
Dipyridyl SCHEMBL3817399 0.80 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8
SCHEMBL314105 0.79 ASIC3 (0.67) ASIC3KDM4ELMNACCR1CCR5
SCHEMBL9132675 0.77 ASIC3 (0.64) ASIC3KDM4ELMNACCR1CCR5
SCHEMBL9151109 0.77 ASIC3 (0.64) ASIC3KDM4ELMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200261896-A1 SYNTHESIS OF PLATINUM SINGLE-SITE CENTERS THROUGH METAL-LIGAND SELF-ASSEMBLY ON METAL OXIDE SUPPORTS UNITED STATES DEPARTMENT OF ENERGY 2020-08-20 US disclosed