SCHEMBL314105

SCHEMBL314105

Nc1ccnc(-c2cc(N)ccn2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 3/20 0.67
CCR1 P32246 3/20 0.48
CCR5 P51681 3/20 0.48
CCR8 P51685 3/20 0.48
SMN1; SMN2 Q16637 4/20 0.43
MAPT P10636 3/20 0.43
LMNA P02545 3/20 0.43
CHRM1 P11229 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 2/20 0.43
CYP2D6 P10635 1/20 0.43
MAPK1 P28482 1/20 0.43
KCNA1 Q09470 1/20 0.43
KDM4C Q9H3R0 2/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132100 0.97 ASIC3 (0.64) ASIC3CCR1CCR5CCR8SMN1; SMN2
SCHEMBL9151109 0.97 ASIC3 (0.64) ASIC3CCR1CCR5CCR8SMN1; SMN2
SCHEMBL9132675 0.97 ASIC3 (0.64) ASIC3CCR1CCR5CCR8SMN1; SMN2
SCHEMBL4361201 0.90 ASIC3 (0.57) ASIC3CCR1CCR5CCR8SMN1; SMN2
Dalfampridine SCHEMBL9979017 0.90 MAPT (0.62) ASIC3CCR1CCR5CCR8SMN1; SMN2
SCHEMBL30173828 0.90 ASIC3 (0.57) ASIC3CCR1CCR5CCR8SMN1; SMN2
SCHEMBL30337333 0.87 ASIC3 (0.79) ASIC3CCR1CCR5CCR8SMN1; SMN2
SCHEMBL21386824 0.86 CCR1 (0.74) ASIC3CCR1CCR5CCR8CHRM1
SCHEMBL30253423 0.86 ASIC3 (0.64) ASIC3CCR1CCR5CCR8SMN1; SMN2
SCHEMBL247730 0.86 ASIC3 (0.64) ASIC3CCR1CCR5CCR8SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217208-A1 CHEMICAL MECHANICAL PLANARIZATION POLISHING FOR INTERCONNECTS DIFFUSION BARRIER MATERIALS VERSUM MATERIALS US, LLC (US) 2025-10-16 WO claimed
WO-2025132825-A1 1H-IMIDAZO[4,5-C]QUINOLINE METAL-BASED COMPLEXES USEFUL AS MEDICAMENTS FUNDACIÓN DONOSTIA INTERNATIONAL PHYSICS CENTER - DIPC (ES) 2025-06-26 WO claimed
CN-119332301-A High-durability composite proton exchange membrane and preparation method thereof 上海恩捷新材料科技有限公司 2025-01-21 CN claimed
US-20230398077-A1 SILICASOME NANOCARRIER FOR METAL-BASED DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-12-14 US claimed
CN-112898349-B Manganese metal complex with 4,4 '-diamino-2, 2' -bipyridine as ligand, and synthetic method and photocatalytic application thereof 云南师范大学 2023-10-03 CN claimed
EP-4237091-A1 A SILICASOME NANOCARRIER FOR METAL-BASED DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-09-06 EP claimed
CN-116606640-A Iridium metal organic compound covalent functionalized graphene oxide ternary nano hybrid material and preparation method thereof 江苏大学 2023-08-18 CN claimed
CN-113968970-B Polyimide film with low thermal expansion coefficient and preparation method and application thereof 浙江中科玖源新材料有限公司 2023-07-07 CN claimed
CN-115677972-A Tough type light-operated self-repairing lignin-based polyurethane and preparation method and application thereof 华南理工大学 2023-02-03 CN claimed
CN-111068787-B Hydrogen peroxide hydrogenation catalyst, preparation method and application thereof 东莞东阳光科研发有限公司 2022-12-27 CN claimed
EP-1349962-A4 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INST OF TECHN (US) 2007-08-08 EP claimed
WO-2007084380-A2 COMPOUNDS AND METHODS FOR NUCLEIC ACID MISMATCH DETECTION CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2007-07-26 WO claimed
US-6808884-B2 INTERCALATION COMPOUND FOR USE IN THE DIAGNOSIS AND DETECTION OF GENETIC DISORDERS CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-10-26 US claimed
WO-2002057492-A9 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INST OF TECHN (US) 2003-12-18 WO claimed
EP-1349962-A1 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-10-08 EP claimed
US-20020155470-A1 Methods and compositions for detecting polynucleotide duplex damage and errors CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-10-24 US claimed
WO-2002057492-A1 METHODS AND COMPOSITIONS FOR DETECTING POLYNUCLEOTIDE DUPLEX DAMAGE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-07-25 WO claimed
EP-0237185-B1 USE OF A PHOTOSENSITIVE CATHODE FOR DEPOSITION OF METAL STRUCTURES WITHIN ORGANIC POLYMERIC FILMS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-01-31 EP claimed
EP-0237185-A1 Use of a photosensitive cathode for deposition of metal structures within organic polymeric films E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-16 EP claimed
US-4657833-A PHOTOSENSITIVE MATERIAL AT INTERFACE OF TRANSPARENT ELECTRODE AND POLYMER FILM E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155470-A1 Methods and compositions for detecting polynucleotide duplex damage and errors POLRMT, POLN, POLM ASIC3 2464/4885CCR1 3874/4885CCR5 4003/4885
US-20230398077-A1 SILICASOME NANOCARRIER FOR METAL-BASED DRUG DELIVERY CD47, SGMS1, ABCC1 ASIC3 1357/4885CCR1 393/4885CCR5 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.