Anthraquinone

Anthraquinone

SCHEMBL22345157

O=C1c2ccccc2C(=O)c2ccccc21.c1c[nH]cn1

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
FKBP5 Q13451 1/20 0.54
MAOA P21397 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CDC25B P30305 2/20 0.50
MAOB P27338 1/20 0.50
POLB P06746 4/20 0.42
RAB9A P51151 4/20 0.42
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
PTPRC P08575 3/20 0.42
APAF1 O14727 3/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
BLM P54132 2/20 0.42
TDP2 O95551 2/20 0.42
NPC1 O15118 2/20 0.42
CES2 O00748 1/20 0.42
TERT O14746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthraquinone SCHEMBL28355802 0.91 ALDH1A1 (0.45) ALDH1A1FKBP5MAOAMEN1KMT2A
Anthrone SCHEMBL28255329 0.86 MAOA (0.60) ALDH1A1FKBP5MAOAMEN1KMT2A
Phthalimide SCHEMBL15948306 0.84 GSK3B (0.58) ALDH1A1FKBP5MAOAMAOBMAPT
Naphthoquinone SCHEMBL20603053 0.84 CDC25B (0.54) ALDH1A1FKBP5MAOAMEN1KMT2A
Phthalic Anhydride SCHEMBL15568926 0.84 TDP1 (0.54) ALDH1A1FKBP5MAOAMEN1KMT2A
Naphthoquinone SCHEMBL29667860 0.84 CDC25B (0.54) ALDH1A1FKBP5MAOAMEN1KMT2A
Menadione SCHEMBL25398650 0.82 ALDH1A1 (0.64) ALDH1A1FKBP5MAOAMEN1KMT2A
Isatin SCHEMBL28191654 0.81 MAOA (0.65) ALDH1A1FKBP5MAOAMAOBMAPT
Acenaphthoquinone SCHEMBL29220671 0.80 ALDH1A1 (0.59) ALDH1A1FKBP5MAOAMEN1KMT2A
Imidazole SCHEMBL25396453 0.78 ALDH1A1 (0.49) ALDH1A1FKBP5MAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108822170-B Anthraquinone benzimidazole nucleoside analogues and synthesis method and application thereof 河南师范大学 2021-08-20 CN claimed
CN-116768801-A Condensed quinone oxime imidazoles and their onium derivatives, their preparation and use 上海交通大学 2023-09-19 CN disclosed
WO-2023168908-A1 FUSED QUINONE OXIME IMIDAZOLE, ONIUM DERIVATIVE THEREOF, PREPARATION THEREFOR AND USE THEREOF 上海交通大学 2023-09-14 WO disclosed
EP-3924430-A1 PHOTOPERIODIC CONTROL OF PHYTOCHROME WITH MATERIALS Lleaf Pty Ltd (AU) 2021-12-22 EP disclosed
CN-108822170-B Anthraquinone benzimidazole nucleoside analogues and synthesis method and application thereof 河南师范大学 2021-08-20 CN disclosed
CN-108822170-B Anthraquinone benzimidazole nucleoside analogues and synthesis method and application thereof 河南师范大学 2021-08-20 CN disclosed
WO-2020163917-A1 PHOTOPERIODIC CONTROL OF PHYTOCHROME WITH MATERIALS Lleaf Pty Ltd (AU) 2020-08-20 WO disclosed
CN-108530365-B 1, 4-naphthoquinone/anthraquinone imidazole derivative and preparation and application thereof 上海交通大学 2020-07-14 CN disclosed