Methacrylic Acid

Methacrylic Acid

SCHEMBL9249508

C=C(C)C(=O)O.C=CCOC(=O)OCC=C

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 4/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 7/20 0.33
HSD17B10 Q99714 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL10901939 0.89 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
Methacrylic Acid SCHEMBL9186775 0.87 TSHR (0.40) TSHRCYP3A4TDP1MAPTCACNA1B
Methacrylic Acid SCHEMBL250051 0.85 TSHR (0.45) TSHRCYP3A4TDP1MAPTCACNA1B
Methacrylic Acid SCHEMBL655219 0.85 TSHR (0.45) TSHRCYP3A4TDP1MAPTCACNA1B
Bicarbonate SCHEMBL10805236 0.84 CYP3A4 (0.45) TSHRCYP3A4TDP1MAPTCACNA1B
Bicarbonate SCHEMBL9658182 0.84 CYP3A4 (0.45) TSHRCYP3A4TDP1MAPTCACNA1B
Bicarbonate SCHEMBL27897261 0.84 CYP3A4 (0.45) TSHRCYP3A4TDP1MAPTCACNA1B
Methacrylic Acid SCHEMBL316282 0.83 TSHR (0.44) TSHRCYP3A4TDP1MAPTCACNA1B
Methacrylic Acid SCHEMBL11017971 0.83 TSHR (0.44) TSHRCYP3A4TDP1MAPTCACNA1B
Methacrylic Acid SCHEMBL9285594 0.83 TSHR (0.38) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0498010-B1 Optical resin articles ALPHA TECHNO CO (JP) 1995-04-26 EP disclosed
US-5147959-A Addition-condensation copolymer KABUSHIKI KAISHA ALPHA GIKEN (JP) 1992-09-15 US disclosed
EP-0498010-A1 Optical resin articles Kabushiki Kaisha Alpha Giken (JP) 1992-08-12 EP disclosed