SCHEMBL22345276

SCHEMBL22345276

COC(=O)CS(=O)(=O)N(C)CCOS(C)(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MMP9 P14780 1/20 0.36
ALOX15 P16050 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31
MMP3 P08254 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28632597 0.83 KDM4E (0.39) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL22345325 0.79 MEN1 (0.39) TSHRKDM4EALDH1A1MEN1KMT2A
SCHEMBL4543902 0.72 TSHR (0.42) TSHRKDM4ELMNAMEN1KMT2A
SCHEMBL795481 0.72 USP2 (0.50) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL5265771 0.70 TSHR (0.52) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL15415189 0.70 TSHR (0.43) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL7305186 0.69 MEN1 (0.40) TSHRALDH1A1LMNAMEN1KMT2A
SCHEMBL17264261 0.69 TSHR (0.43) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL7309475 0.69 MMP3 (0.60) TSHRALDH1A1LMNACA12CA14
SCHEMBL14497716 0.67 USP2 (0.55) TSHRKDM4EUSP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220104492-A1 PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH SYNGENTA CROP PROTECTION AG (CH) 2022-04-07 US disclosed
EP-3924347-A1 PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH Syngenta Crop Protection AG (CH) 2021-12-22 EP disclosed
CN-113439081-A Pyridazinium compounds for use in methods of controlling unwanted plant growth 先正达农作物保护股份公司 2021-09-24 CN disclosed
WO-2020164973-A1 PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220104492-A1 PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH DDT, PNPO, PLPBP TSHR 301/4885KDM4E 1228/4885USP2 2069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.