SCHEMBL2234580

SCHEMBL2234580

CCC(C=CC(=O)O)[Si](OC)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38
GABRG1 Q8N1C3 2/20 0.38
GABRG3 Q99928 2/20 0.38
GABRQ Q9UN88 2/20 0.38
HCAR2 Q8TDS4 7/20 0.35
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2262727 1.00 GABRP (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5371956 0.83 HCAR2 (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL5371946 0.83 HCAR2 (0.38) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1848877 0.74 GABRP (0.46) GABRPGABRDGABRA1GABRB1GABRG2
Maleic Acid SCHEMBL28560767 0.73 HCAR2 (0.39) HCAR2
Fumaric Acid SCHEMBL1967229 0.72 HCAR2 (0.38) HCAR2
SCHEMBL516392 0.72 APEX1 (0.30)
SCHEMBL516393 0.72 APEX1 (0.30)
SCHEMBL2455717 0.70 TSHR (0.30)
SCHEMBL4829243 0.68 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10012904-B2 Lithographic printing plate precursors and coating Mark'Andy Inc. (US) 2018-07-03 US claimed
EP-3063591-B1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND COATING ANOCOIL CORP (US) 2018-04-04 EP claimed
US-20160252813-A1 Lithographic Printing Plate Precursors and Coating VERICO TECHNOLOGY LLC 2016-09-01 US claimed
US-7534315-B1 Method for dialysis on microchips using thin porous polymer membrane SANDIA CORPORATION (US) 2009-05-19 US claimed
US-7264723-B2 Dialysis on microchips using thin porous polymer membranes SANDIA CORPORATION (US) 2007-09-04 US claimed
US-20040084370-A1 Dialysis on microchips using thin porous polymer membranes NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2004-05-06 US claimed
US-10012904-B2 Lithographic printing plate precursors and coating Mark'Andy Inc. (US) 2018-07-03 US disclosed
EP-3063591-B1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND COATING ANOCOIL CORP (US) 2018-04-04 EP disclosed
EP-3063591-A1 LITHOGRAPHIC PRINTING PLATE PRECURSORS AND COATING Anocoil Corporation (US) 2016-09-07 EP disclosed
US-20160252813-A1 Lithographic Printing Plate Precursors and Coating VERICO TECHNOLOGY LLC 2016-09-01 US disclosed
US-8242299-B2 Non-shrinkable sol-gel-polymer hybrid and methods thereof CORNING INCORPORATED (US) 2012-08-14 US disclosed
EP-2361942-A1 Non-shrinkable sol-gel-polymer hybrid and methods thereof Corning Incorporated (US) 2011-08-31 EP disclosed
US-20110207206-A1 NON-SHRINKABLE SOL-GEL-POLYMER HYBRID AND METHODS THEREOF CORNING INCORPORATED 2011-08-25 US disclosed
US-7828948-B1 Preconcentration and separation of analytes in microchannels SANDIA CORPORATION (US) 2010-11-09 US disclosed
US-7754077-B1 Dialysis membrane for separation on microchips SANDIA CORPORATION (US) 2010-07-13 US disclosed
US-7534315-B1 Method for dialysis on microchips using thin porous polymer membrane SANDIA CORPORATION (US) 2009-05-19 US disclosed
US-7264723-B2 Dialysis on microchips using thin porous polymer membranes SANDIA CORPORATION (US) 2007-09-04 US disclosed
US-7157530-B2 Catalyst system for controlled polymerization CARNEGIE MELLON UNIVERSITY (US) 2007-01-02 US disclosed
US-20040084370-A1 Dialysis on microchips using thin porous polymer membranes NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2004-05-06 US disclosed
WO-2001062803-A2 SUPPORTED CATALYSTS FOR USE IN ATOM TRANSFER RADICAL POLYMERIZATION AND CONTINUOUS PROCESSES FOR ATOM TRANSFER RADICAL POLYMERIZATION MCMASTER UNIVERSITY (CA) 2001-08-30 WO disclosed