Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CMA1 | P23946 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3304505 | 1.00 | GPR84 (0.51) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL27663008 | 0.99 | GPR84 (0.50) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| SCHEMBL28406976 | 0.99 | GPR84 (0.50) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| Iodide SCHEMBL28079826 | 0.97 | GPR84 (0.49) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL27640400 | 0.97 | GPR84 (0.49) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| SCHEMBL27693089 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTRECQLCA2MEN1 | |
| SCHEMBL4297919 | 0.82 | HDAC3 (0.44) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| SCHEMBL25469062 | 0.81 | GPR84 (0.56) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| SCHEMBL9275407 | 0.81 | GPR84 (0.56) | GPR84KDM4ECMA1HPGDHSD17B10 | |
| SCHEMBL18413853 | 0.81 | GPR84 (0.56) | GPR84KDM4ECMA1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020166592-A1 | HEMIASTERLIN DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | 大日本住友製薬株式会社 | 2020-08-20 | — | — | WO | disclosed |
| WO-2020166600-A1 | HEMIASTERLIN DERIVATIVE HAVING CYSTEINE RESIDUE | 大日本住友製薬株式会社 | 2020-08-20 | — | — | WO | disclosed |