Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.48 |
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL58075 | 0.93 | CTSS (0.47) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL89265 | 0.93 | CTSS (0.47) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL5024738 | 0.89 | CTSS (0.49) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL58394 | 0.89 | CTSS (0.49) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL57550 | 0.89 | CTSS (0.49) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL6671005 | 0.87 | CTSS (0.47) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL9963924 | 0.81 | CTSS (0.52) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL18405913 | 0.81 | CTSS (0.52) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL18932855 | 0.81 | PPARA (0.43) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL18932852 | 0.80 | PPARA (0.42) | CTSSCTSKCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020166592-A1 | HEMIASTERLIN DERIVATIVE AND ANTIBODY-DRUG CONJUGATE THEREOF | 大日本住友製薬株式会社 | 2020-08-20 | — | — | WO | disclosed |
| WO-2020166600-A1 | HEMIASTERLIN DERIVATIVE HAVING CYSTEINE RESIDUE | 大日本住友製薬株式会社 | 2020-08-20 | — | — | WO | disclosed |