Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 9/20 | 0.47 |
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024738 | 0.88 | CTSS (0.49) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL58394 | 0.88 | CTSS (0.49) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL57550 | 0.88 | CTSS (0.49) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL22345951 | 0.87 | CTSS (0.48) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL58075 | 0.85 | CTSS (0.47) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL89265 | 0.85 | CTSS (0.47) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL18405913 | 0.80 | CTSS (0.52) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL9963924 | 0.80 | CTSS (0.52) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL13342905 | 0.79 | PPARA (0.46) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL1791975 | 0.79 | CTSS (0.44) | CTSSCTSKCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026293-A2 | HEMIASTERLIN DERIVATIVES FOR TREATING RESISTANT TUMORS | WYETH HOLDINGS CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |