Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL28946100 | 0.98 | CYP3A4 (0.59) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL14742052 | 0.88 | LMNA (0.52) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL2787343 | 0.88 | LMNA (0.57) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Valine SCHEMBL28202877 | 0.87 | SLC7A5 (0.60) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL29441891 | 0.86 | LMNA (0.50) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL3820379 | 0.86 | MEN1 (0.55) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Threonine SCHEMBL28187537 | 0.86 | LMNA (0.44) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL1683101 | 0.85 | KMT2A (0.48) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL1683106 | 0.85 | KMT2A (0.48) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Leucine SCHEMBL28252682 | 0.84 | SLC7A5 (0.67) | LMNAMEN1KMT2ACYP3A4SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116285016-B | Starch-based composite foam material and preparation and application thereof | 中国科学院长春应用化学研究所 | 2025-05-20 | — | — | CN | claimed |
| CN-114621984-B | Method for synthesizing 1, 5-pentanediamine by using ionic liquid to strengthen lysine decarboxylase | 中国科学院过程工程研究所 | 2025-01-28 | — | — | CN | claimed |
| CN-116656753-A | Efficient and continuous phospholipid type arachidonic acid enzymatic method | 江南大学 | 2023-08-29 | — | — | CN | claimed |
| CN-116285016-A | Starch-based composite foam material and preparation and application thereof | 中国科学院长春应用化学研究所 | 2023-06-23 | — | — | CN | claimed |
| CN-114982746-B | Preparation method for synthesizing gold nanoflower antibacterial agent based on food-borne ionic liquid | 中国海洋大学 | 2023-03-21 | — | — | CN | claimed |
| CN-114982746-A | Preparation method for synthesizing gold nanoflowers antibacterial agent based on food-borne ionic liquid | 中国海洋大学 | 2022-09-02 | — | — | CN | claimed |
| CN-114621984-A | Method for synthesizing 1, 5-pentanediamine by strengthening lysine decarboxylase through ionic liquid | 中国科学院过程工程研究所 | 2022-06-14 | — | — | CN | claimed |
| CN-114426992-A | Amino functionalized ionic liquid reinforced CO2Biotransformation process | 中国科学院过程工程研究所 | 2022-05-03 | — | — | CN | claimed |
| CN-112646613-A | Absorbent and method for separating and recovering carbon dioxide in blast furnace gas | 中石化南京化工研究院有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-108794652-B | Chitin integrated production system and processing method thereof | 中国科学院过程工程研究所 | 2021-02-05 | — | — | CN | claimed |
| CN-109627122-A | A kind of biogas residue farmland compound fertilizer and preparation method thereof | 山东省农业科学院作物研究所 | 2019-04-16 | — | — | CN | claimed |
| CN-108794652-A | A kind of chitin integraterd manufacturing system and its processing method | 中国科学院过程工程研究所 | 2018-11-13 | — | — | CN | claimed |
| CN-107778347-A | It is a kind of using amino acid ion liquid from silkworm chrysalis separated and dissolved pupa albumen method | 中国科学院过程工程研究所 | 2018-03-09 | — | — | CN | claimed |
| CN-107573401-A | The method that ion liquid solvent system dissolving fermentation bacteria residue prepares high polymer | 中国科学院过程工程研究所 | 2018-01-12 | — | — | CN | claimed |
| CN-104437008-A | Method for preparing biological methane by purifying and purifying biogas | NANJING UNIVERSITY OF TECHNOLOGY | 2015-03-25 | — | — | CN | claimed |
| US-20250260180-A1 | COMPACT THREE-DIMENSIONAL ULTRA-WIDEBAND ANTENNA WITH IMPROVED CIRCULAR POLARIZATION PURITY | NOVATEL INC. (CA) | 2025-08-14 | — | — | US | disclosed |
| EP-4601122-A1 | COMPACT THREE-DIMENSIONAL ULTRA-WIDEBAND ANTENNA WITH IMPROVED CIRCULAR POLARIZATION PURITY | Novatel, Inc. (CA) | 2025-08-13 | — | — | EP | disclosed |
| CN-107427546-A | Composition containing extract of discorea nipponica and its medicinal use | 师沛恩生技有限责任公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107312109-A | Chitin separating and extracting process in a kind of shrimp and crab shells based on degradable ionic liquid | 中国科学院过程工程研究所 | 2017-11-03 | — | — | CN | disclosed |
| CN-104437008-A | Method for preparing biological methane by purifying and purifying biogas | NANJING UNIVERSITY OF TECHNOLOGY | 2015-03-25 | — | — | CN | disclosed |