SCHEMBL22346231

SCHEMBL22346231

CC1(C)C=Cc2cc[nH]c2C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14502429 0.63
SCHEMBL19020583 0.61
SCHEMBL12377 0.60
SCHEMBL23136580 0.58
SCHEMBL10560679 0.58 HTR2C (0.36)
SCHEMBL8616260 0.58 NOS3 (0.34) NOS3NOS2
SCHEMBL23432605 0.58
SCHEMBL21350103 0.58
SCHEMBL4801046 0.58 NOS3 (0.31) NOS3NOS2
SCHEMBL31425525 0.58 NOS3 (0.34) NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103880862-A Inhibitors Of Hepatitis C Virus Replication MERCK SHARP & DOHME 2014-06-25 CN claimed
CN-100340632-C Method for roughening copper surfaces for bonding to substrates ELECTROCHEMICALS INC (US) 2007-10-03 CN claimed
CN-1079395-C Production method of N-acetyl-5, 6-dimethoxytryptamine TAN DUNXIAN (CN) 2002-02-20 CN claimed
CN-1051668-A Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out OREAL (FR) 1991-05-29 CN claimed
WO-2020166705-A1 PRODUCTION METHOD FOR OLIGONUCLEOTIDES 味の素株式会社 2020-08-20 WO disclosed
CN-106749275-B It is a kind of using Quinazol derivative as the compound of core and its application on OLED 江苏三月光电科技有限公司 2019-04-19 CN disclosed
CN-106749274-B A kind of compound that parent nucleus is Quinazol derivative and its application on OLED 江苏三月光电科技有限公司 2019-01-08 CN disclosed
CN-106699763-B It is a kind of using Quinazol derivative as the compound of core and its application 江苏三月光电科技有限公司 2019-01-08 CN disclosed
CN-106749275-A A kind of compound with Quinazol derivative as core and its application on OLED 江苏三月光电科技有限公司 2017-05-31 CN disclosed
CN-106699763-A Chemical compound taking quinazolinone derivative as core and application of chemical compound 江苏三月光电科技有限公司 2017-05-24 CN disclosed
CN-102617443-A Optically active indole derivative, synthetic method and application thereof UNIV EAST CHINA NORMAL 2012-08-01 CN disclosed
CN-102503881-A Optically active tryptamine derivative and synthetic method and application thereof UNIV EAST CHINA NORMAL 2012-06-20 CN disclosed
CN-1193018-C New heterocyclic derivative and its medical use KYOTO PHARMACEUTICAL CO LTD (JP) 2005-03-16 CN disclosed
CN-1501914-A Indoline derivative and process for producing the same ������������ʽ���� 2004-06-02 CN disclosed
CN-1451031-A Method for roughening copper surfaces for bonding to substrates ELECTROCHEMICALS INC (US) 2003-10-22 CN disclosed
CN-1097043-C novel heterocyclic derivatives and medicinal use thereof KYOTO PHARMA IND (JP) 2002-12-25 CN disclosed
CN-1361100-A New heterocyclic derivative and its medical use KYOTO PHARMACEUTICAL CO LTD (JP) 2002-07-31 CN disclosed
CN-1203587-A Novel heterocyclic derivatives and medicinal use thereof KYOTO PHARMA IND (JP) 1998-12-30 CN disclosed
CN-1148340-A Treatment of 5HTZBMethods of receptor-related disorders LILLY CO ELI (US) 1997-04-23 CN disclosed
CN-1051668-A Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out OREAL (FR) 1991-05-29 CN disclosed