SCHEMBL8616260

SCHEMBL8616260

CC1(C)C=Cc2[c]n[nH]c2C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8610888 0.70 NOS3 (0.34) NOS3NOS2
SCHEMBL27648942 0.64 NOS3 (0.35) NOS3NOS2
SCHEMBL27778995 0.63 NOS3 (0.34) NOS3NOS2
SCHEMBL27557564 0.60 NOS3 (0.35) NOS3NOS2
SCHEMBL22346231 0.58 NOS3 (0.32) NOS3NOS2
SCHEMBL28148883 0.56 NOS3 (0.31) NOS3NOS2
SCHEMBL1536047 0.54
SCHEMBL22203157 0.52 NOS3 (0.31) NOS3NOS2
SCHEMBL28327392 0.52 CYP3A4 (0.39) NOS3NOS2
SCHEMBL19337502 0.50 NOS3 (0.36) NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0835242-A1 THIOAMIDES S-OXIDES FOR USE AS PESTICIDES Novartis AG (CH) 1998-04-15 EP disclosed
WO-1997000859-A1 THIOAMIDES S-OXIDES FOR USE AS PESTICIDES NOVARTIS AG (CH) 1997-01-09 WO disclosed