⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088493 | 0.77 | — | — | |
| SCHEMBL4179634 | 0.75 | — | — | |
| SCHEMBL18209929 | 0.75 | MTNR1A (0.33) | — | |
| SCHEMBL22346404 | 0.75 | — | — | |
| SCHEMBL4725865 | 0.75 | MTNR1A (0.33) | — | |
| SCHEMBL4970087 | 0.75 | — | — | |
| SCHEMBL16823509 | 0.73 | — | — | |
| SCHEMBL16823510 | 0.73 | — | — | |
| SCHEMBL15756698 | 0.72 | MLYCD (0.33) | — | |
| SCHEMBL3281867 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924049-A1 | THIOENO[3,2-B] PYRIDIN-7-AMINE COMPOUNDS FOR TREATING FAMILIAL DYSAUTONOMIA | PTC Therapeutics, Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020167628-A1 | THIOENO[3,2-B] PYRIDIN-7-AMINE COMPOUNDS FOR TREATING FAMILIAL DYSAUTONOMIA | PTC THERAPEUTICS, INC. (US) | 2020-08-20 | — | — | WO | disclosed |